Formal Concept Analysis of Disease Similarity

@inproceedings{Keller2012FormalCA,
  title={Formal Concept Analysis of Disease Similarity},
  author={Benjamin J. Keller and Felix Eichinger and Matthias Kretzler},
  booktitle={AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science},
  year={2012}
}
Previous work shows that gene associations and network properties common between pairs of diseases can provide molecular evidence of comorbidity, but relationships among diseases may extend to larger groups. Formal concept analysis allows the study of multiple diseases based on a concept lattice whose structure indicates gene set commonality. We use the concept lattice for gene associations to evaluate the complexity of the relationships among diseases, and to identify concepts whose gene sets… CONTINUE READING
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