Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence

@article{Junt2008FormFF,
  title={Form follows function: lymphoid tissue microarchitecture in antimicrobial immune defence},
  author={Tobias Junt and Elke Scandella and Burkhard Ludewig},
  journal={Nature Reviews Immunology},
  year={2008},
  volume={8},
  pages={764-775}
}
Secondary lymphoid organs (SLOs) are tissues that facilitate the induction of adaptive immune responses. These organs capture pathogens to limit their spread throughout the body, bring antigen-presenting cells into productive contact with their cognate lymphocytes and provide niches for the differentiation of immune effector cells. Therefore, the microanatomy of SLOs defines the ability of an organism to respond to pathogens. SLO microarchitecture is, at the same time, extremely adaptable to… CONTINUE READING

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References

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SHOWING 1-10 OF 125 REFERENCES

Inhibition of the lymphotoxin pathway as a therapy for autoimmune disease

J. L. Browning
  • Immunol. Rev. 223,
  • 2008