Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene.

@article{Pisarska2004ForkheadLI,
  title={Forkhead l2 is expressed in the ovary and represses the promoter activity of the steroidogenic acute regulatory gene.},
  author={Margareta D Pisarska and Jeehyeon Bae and Cynthia A Klein and Aaron J Hsueh},
  journal={Endocrinology},
  year={2004},
  volume={145 7},
  pages={3424-33}
}
Premature ovarian failure in a subgroup of women with blepharophimosis-ptosis-epicanthus inversus type 1 syndrome has been associated with nonsense mutations in the gene encoding a Forkhead transcription factor, Forkhead L2 (FOXL2). However, the exact function of FOXL2 in the ovary is unclear. We investigated the expression of FOXL2 in the mouse ovary during follicular development and maturation by RT-PCR and in situ hybridization. The FOXL2 mRNA is expressed in ovaries throughout development… CONTINUE READING

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