Forkhead box A1 (FOXA1) tagging polymorphisms and esophageal cancer risk in a Chinese population: a fine-mapping study.

@article{Li2016ForkheadBA,
  title={Forkhead box A1 (FOXA1) tagging polymorphisms and esophageal cancer risk in a Chinese population: a fine-mapping study.},
  author={Mingna Li and Wenbo Zhang and Chao Yuan Liu and Yijun Shi and Weifeng Tang and Suocheng Chen and Haiyong Gu and Jun Yin and Zhi-hong Zhang and Pengcheng Jiang},
  journal={Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals},
  year={2016},
  volume={21 6},
  pages={523-9}
}
Esophageal cancer was the fifth most commonly diagnosed cancer and the fourth leading cause of cancer-related death in China in 2009. Esophageal squamous cell carcinoma (ESCC) accounts for more than 90% of esophageal cancers. Besides environmental risk factors, genetic factors such as single-nucleotide polymorphisms (SNPs) play an important role in ESCC carcinogenesis. We performed a hospital-based case-control study to evaluate the Forkhead-box protein A1 (FOXA1) rs12894364 C > T, rs2145146 C… CONTINUE READING

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