• DOI:10.1002/cpt1979263294
Corpus ID: 41194071

Forecasting individual pharmacokinetics

@article{Sheiner1979ForecastingIP,
  title={Forecasting individual pharmacokinetics},
  author={L. Sheiner and S. Beal and B. Rosenberg and V. V. Marathe},
  journal={Clinical Pharmacology & Therapeutics},
  year={1979},
  volume={26}
}

L. Sheiner, S. Beal, +1 author V. V. Marathe

Published 1979

Medicine

Clinical Pharmacology & Therapeutics

Often drug dosage may be chosen rationally by use of plasma concentration (CP) as the “therapeutic” end point. The ability to accurately forecast the CP resulting from a dosage regimen is central to choosing that regimen. Traditionally forecasting has been attempted only by accounting for known influences on pharmacokinetics, such as sex, age, and renal disease. One must also adjust for previously observed CPs. Herein, we discuss and explain an approach to both of these tasks, mainly focusing… CONTINUE READING

View on Wiley

ncbi.nlm.nih.gov

Save to Library

Create Alert

Cite

Launch Research Feed