Forces and Bond Dynamics in Cell Adhesion

@article{Evans2007ForcesAB,
  title={Forces and Bond Dynamics in Cell Adhesion},
  author={E. Evans and D. Calderwood},
  journal={Science},
  year={2007},
  volume={316},
  pages={1148 - 1153}
}
  • E. Evans, D. Calderwood
  • Published 2007
  • Chemistry, Medicine
  • Science
  • Adhesion of a biological cell to another cell or the extracellular matrix involves complex couplings between cell biochemistry, structural mechanics, and surface bonding. The interactions are dynamic and act through association and dissociation of bonds between very large molecules at rates that change considerably under stress. Combining molecular cell biology with single-molecule force spectroscopy provides a powerful tool for exploring the complexity of cell adhesion, that is, how cell… CONTINUE READING

    Topics from this paper.

    Citations

    Publications citing this paper.
    SHOWING 1-10 OF 405 CITATIONS, ESTIMATED 61% COVERAGE

    Friction-controlled traction force in cell adhesion.

    Biophysics of Cell-Substrate Interactions Under Shear

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Force distribution on multiple bonds controls the kinetics of adhesion in stretched cells.

    VIEW 1 EXCERPT
    CITES BACKGROUND

    Modeling Active Mechanosensing in Cell-Matrix Interactions.

    VIEW 2 EXCERPTS
    CITES BACKGROUND

    Single-cell force spectroscopy

    VIEW 2 EXCERPTS
    CITES BACKGROUND

    FILTER CITATIONS BY YEAR

    2007
    2020

    CITATION STATISTICS

    • 10 Highly Influenced Citations

    • Averaged 17 Citations per year from 2018 through 2020

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 66 REFERENCES

    Blood.

    • P. Sperryn
    • Medicine
    • British journal of sports medicine
    • 1989

    Immunity

    Nature

    • Richard M Rosenfeld
    • Medicine
    • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
    • 2009

    Proc

    • Natl. Acad. Sci. U.S.A. 101,
    VIEW 4 EXCERPTS
    HIGHLY INFLUENTIAL

    Acting as a soft spring linked in series with the probe

    • Acting as a soft spring linked in series with the probe

    Annu. Rev. Biomed. Eng

    • Annu. Rev. Biomed. Eng
    • 2006

    Annu. Rev. Biophys. Biomol. Struct

    • Annu. Rev. Biophys. Biomol. Struct
    • 2006

    Annu. Rev. Cell Dev. Biol

    • Annu. Rev. Cell Dev. Biol
    • 2005

    Biophys. J

    • Biophys. J
    • 2006