Forced swimming stimulates the expression of vasopressin and oxytocin in magnocellular neurons of the rat hypothalamic paraventricular nucleus.

@article{Wotjak2001ForcedSS,
  title={Forced swimming stimulates the expression of vasopressin and oxytocin in magnocellular neurons of the rat hypothalamic paraventricular nucleus.},
  author={Carsten T. Wotjak and Takako Naruo and Shogo Muraoka and R Simchen and Rainer Landgraf and Mario Engelmann},
  journal={The European journal of neuroscience},
  year={2001},
  volume={13 12},
  pages={2273-81}
}
Previous studies have shown that a 10-min forced swimming session triggers the release of both vasopressin and oxytocin into the extracellular fluid of the hypothalamic paraventricular (PVN) and supraoptic nuclei (SON) in rats. At the same time oxytocin, but not vasopressin, was released from the axon terminals into the blood. Here we combined forced swimming with in situ hybridization to investigate whether (i) the stressor-induced release of vasopressin and oxytocin within the PVN originates… CONTINUE READING

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