Force-velocity relation in chemically skinned rat portal vein

  title={Force-velocity relation in chemically skinned rat portal vein},
  author={Anders Arner},
  journal={Pfl{\"u}gers Archiv},
Rat portal veins were chemically skinned using Triton X-100 and mounted for isometric and quick release experiments at 20°C. The skinned preparations were activated by Ca2+ (EGTA-buffered) in solutions containing 2 mM free-Mg2+ and 1 μM calmodulin. Half maximal isometric force was obtained at pCa=6.2. Maximal force of the skinned preparations, at pCa=4.5, was 8.2±0.8 mN/mm2 (n=6). Force-velocity relations were determined at varied Ca2+-concentrations. Maximal shortening velocity (V max) was 0… CONTINUE READING

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 20 extracted citations

Calcium and Contractility

View 7 Excerpts
Highly Influenced

Mechanical alterations in smooth muscle from mice lacking desmin

Journal of Muscle Research & Cell Motility • 1998
View 1 Excerpt


Publications referenced by this paper.
Showing 1-10 of 41 references

Calcium dependence of force and velocity in vascular smooth muscle

PF Dillon
Fed Proc • 1980
View 1 Excerpt

Similar Papers

Loading similar papers…