Force-velocity-length relationship in heart muscle: Lack of time-independence during twitch contractions of frog ventricle strips with caffeine

@article{Henderson1974ForcevelocitylengthRI,
  title={Force-velocity-length relationship in heart muscle: Lack of time-independence during twitch contractions of frog ventricle strips with caffeine},
  author={Andrew H. Henderson and Dirk L. Brutsaert},
  journal={Pfl{\"u}gers Archiv},
  year={1974},
  volume={348},
  pages={59-64}
}
It has been demonstrated previously that the force-velocity-length (FVL) relationship in twitch contractions of mammalian heart muscle is independent of time during a major portion of the shortening phase of the contractions. These findings were confirmed under all conditions studied. The reason for the phenomenon is not established. In the present study the time course of the FVL relationship has been examined in twitch contractions of amphibian heart muscle. Caffeine shortens the duration of… CONTINUE READING

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