Force generation, transmission, and integration during cell and tissue morphogenesis.

  title={Force generation, transmission, and integration during cell and tissue morphogenesis.},
  author={Thomas Lecuit and Pierre-François Lenne and Edwin Munro},
  journal={Annual review of cell and developmental biology},
Cell shape changes underlie a large set of biological processes ranging from cell division to cell motility. Stereotyped patterns of cell shape changes also determine tissue remodeling events such as extension or invagination. In vitro and cell culture systems have been essential to understanding the fundamental physical principles of subcellular mechanics. These are now complemented by studies in developing organisms that emphasize how cell and tissue morphogenesis emerge from the interplay… CONTINUE READING

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