Force differentiation in recognition of cross-reactive antigens by magnetic beads.

@article{Morozova2008ForceDI,
  title={Force differentiation in recognition of cross-reactive antigens by magnetic beads.},
  author={Tamara Ya Morozova and Victor N. Morozov},
  journal={Analytical biochemistry},
  year={2008},
  volume={374 2},
  pages={263-71}
}
Functionalized magnetic beads have been suggested recently as active labels for extremely rapid and highly sensitive immunoassay. Here we addressed the problem of specificity and cross-reactivity in such detection, which (unlike conventional immunoassay methods) cannot rely on a difference in the equilibrium binding constants to distinguish between closely related antigens. Microarrays containing spots of nine albumins from sera of different mammals (human, bovine, sheep, goat, pig, dog, rabbit… CONTINUE READING