Force and focal adhesion assembly: a close relationship studied using elastic micropatterned substrates

Abstract

Mechanical forces play a major role in the regulation of cell adhesion and cytoskeletal organization. In order to explore the molecular mechanism underlying this regulation, we have investigated the relationship between local force applied by the cell to the substrate and the assembly of focal adhesions. A novel approach was developed for real-time, high… (More)
DOI: 10.1038/35074532

5 Figures and Tables

Topics

  • Presentations referencing similar topics