Force-Induced Calcium Concentration Change and Focal Adhesion Translocation: Effects of Force Amplitude and Frequency

Vascular endothelial cells rapidly sense and transduce external forces into biological signals through a process known as mechanotransduction. Numerous biological processes are involved in mechanotransduction, including calcium signaling and activation of focal adhesion sites, but little is known about how cells initially sense changes in the external… CONTINUE READING