Force Generation upon T Cell Receptor Engagement

@inproceedings{Husson2011ForceGU,
  title={Force Generation upon T Cell Receptor Engagement},
  author={Julien Husson and Karine Chemin and Armelle Bohineust and Claire Hivroz and Nelly Henry},
  booktitle={PloS one},
  year={2011}
}
T cells are major players of adaptive immune response in mammals. Recognition of an antigenic peptide in association with the major histocompatibility complex at the surface of an antigen presenting cell (APC) is a specific and sensitive process whose mechanism is not fully understood. The potential contribution of mechanical forces in the T cell activation process is increasingly debated, although these forces are scarcely defined and hold only limited experimental evidence. In this work, we… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 56 references

Real-time single-cell response to stiffness.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 1 Excerpt

Simulation of cell motility that reproduces the force-velocity relationship.

Proceedings of the National Academy of Sciences of the United States of America • 2010
View 1 Excerpt

Single-cell response to stiffness exhibits muscle-like behavior.

Proceedings of the National Academy of Sciences of the United States of America • 2009
View 2 Excerpts

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