For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection.

@article{Dorhoi2011ForBO,
  title={For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection.},
  author={Anca Dorhoi and Stephen T. Reece and Stefan H. E. Kaufmann},
  journal={Immunological reviews},
  year={2011},
  volume={240 1},
  pages={235-51}
}
Tuberculosis (TB) is a complex disease, and the success of the bacterium as an intracellular pathogen is the outcome of its close and longstanding coevolution with the mammalian host. The dialogue between Mycobacterium tuberculosis and the host is becoming understandable at the molecular, cellular, and tissue level. This has led to the elucidation of the (i) interaction between pattern recognition receptors and pathogen-associated molecular patterns, (ii) cross-talk between immune cells, and… CONTINUE READING