For X-irradiated normal human fibroblasts, only half of cell inactivation results from chromosomal damage.

Abstract

PURPOSE To study the relationship between residual double-strand breaks (dsbs), chromosomal damage, and cell inactivation for X-irradiated normal human fibroblasts. METHODS AND MATERIALS The experiments were performed with 12 normal human fibroblast strains and, for comparison, a fibroblast line from a LiFraumeni patient (LFS2800), a squamous cell… (More)

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