Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species

  title={Footprints of ancient-balanced polymorphisms in genetic variation data from closely related species},
  author={Ziyue Gao and Molly Przeworski and Guy Sella},
  journal={Evolution; International Journal of Organic Evolution},
  pages={431 - 446}
When long‐lasting, balancing selection can lead to “trans‐species” polymorphisms that are shared by two or more species identical by descent. In such cases, the gene genealogy at the selected site clusters by allele instead of by species, and nearby neutral sites also have unusual genealogies because of linkage. While this scenario is expected to leave discernible footprints in genetic variation data, the specific patterns remain poorly characterized. Motivated by recent findings in primates… 

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