Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins.

@article{Pulido2007FootandmouthDV,
  title={Foot-and-mouth disease virus infection induces proteolytic cleavage of PTB, eIF3a,b, and PABP RNA-binding proteins.},
  author={Miguel Rodr{\'i}guez Pulido and Paula Carolina Serrano and Margarita S{\'a}iz and Encarnaci{\'o}n Mart{\'i}nez-Salas},
  journal={Virology},
  year={2007},
  volume={364 2},
  pages={466-74}
}
Foot-and-mouth disease virus (FMDV) infection induces major changes in the host cell including the shutoff of cellular protein synthesis. Here, protein extracts from FMDV-infected cells have been used to monitor changes in the profile of RNA-binding factors interacting with regulatory regions of the viral RNA. Relevant differences have been detected in the pattern of interaction with proteins prepared from either infected or uninfected cells with RNA probes encompassing the internal ribosome… CONTINUE READING