Foot-and-mouth disease virus: Plaque reduction neutralization test

@article{McVicar2005FootandmouthDV,
  title={Foot-and-mouth disease virus: Plaque reduction neutralization test},
  author={John W. McVicar and Paul Sutmoller and Arthur A. Andersen},
  journal={Archiv f{\"u}r die gesamte Virusforschung},
  year={2005},
  volume={44},
  pages={168-172}
}
Studies of the transmission and pathogenesis of foot-and-mouth disease (FMD) require a method of quantitating the neutralizing activity of a number of body fluids in order to assess an animal's response to infection or immunization. These studies usually generate large numbers of a variety of samples from each animal including serum, oesophageal-pharyngeal fluid (8), nasal mucus, and lacrimal fluid. The standard virus-varying serum (PDs0) neutralization test in suckling mice (3) is time… CONTINUE READING
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