Food vacuole proteome of the malarial parasite Plasmodium falciparum.

  title={Food vacuole proteome of the malarial parasite Plasmodium falciparum.},
  author={Mauld H Lamarque and Christophe Tastet and Jo{\"e}l Poncet and Edith Demettre and Patrick Jouin and Henri J. Vial and J F Dubremetz},
  journal={Proteomics. Clinical applications},
  volume={2 9},
The Plasmodium falciparum food vacuole (FV) is a lysosome-like organelle where erythrocyte hemoglobin digestion occurs. It is a favorite target in the development of antimalarials. We have used a tandem mass spectrometry approach to investigate the proteome of an FV-enriched fraction and identified 116 proteins. The electron microscopy analysis and the Western blot data showed that the major component of the fraction was the FV and, as expected, the majority of previously known FV markers were… CONTINUE READING
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