Food storage material silver nanoparticles interfere with DNA replication fidelity and bind with DNA.

@article{Yang2009FoodSM,
  title={Food storage material silver nanoparticles interfere with DNA replication fidelity and bind with DNA.},
  author={Wenjuan Yang and Cenchao Shen and Qiaoli Ji and Hongjie An and Jinju Wang and Qingdai Liu and Zhizhou Zhang},
  journal={Nanotechnology},
  year={2009},
  volume={20 8},
  pages={085102}
}
Nanosilver is increasingly used in the food industry and biomedical applications. A lot of studies have been done to investigate the potential toxicity of nanosilver. But information on whether or how nanosilver particles bring changes in genetic materials remains scant. In this study, the replication fidelity of the rpsL gene was quantified when nanosilver particles were present in polymerase chain reactions (PCRs) or cell cultures of E. coli transformed with the wild-type rpsL gene. Three… CONTINUE READING
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