Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and DeltaFosB expression in the nucleus accumbens of the rat.

@article{Stamp2008FoodRE,
  title={Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and DeltaFosB expression in the nucleus accumbens of the rat.},
  author={Jennifer A Stamp and Rahia Mashoodh and Jackalina M Van Kampen and Harold A. Robertson},
  journal={Brain research},
  year={2008},
  volume={1204},
  pages={94-101}
}
Chronic stress has been known to potentiate addictive behaviours in both human addicts and experimental animals. In the present study, chronic mild food restriction was used as a stressor to investigate its effect on the locomotor simulant effects of cocaine as well as FosB expression in the nucleus accumbens and caudate putamen. Chronic mild food restriction enhanced the locomotor response to the first cocaine injection, such that chronically food restricted animals showed a significant… CONTINUE READING

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