Food does not affect the bioavailability of baclofen.

  title={Food does not affect the bioavailability of baclofen.},
  author={Gregory M Peterson and Sarah McLean and K. S. Millingen},
  journal={The Medical journal of Australia},
  volume={142 13},
It is recommended that baclofen, a centrally acting muscle relaxant, be administered with food or milk to minimize its gastrointestinal side-effects. However, there are no published data on the influence of food on the bioavailability of the drug. The extent and rate of absorption of baclofen were investigated after the oral administration of single 20-mg doses to five healthy volunteers. The drug was administered either under fasting conditions or with a standard meal, according to a crossover… CONTINUE READING