Food-derived peptides stimulate mucin secretion and gene expression in intestinal cells.

  title={Food-derived peptides stimulate mucin secretion and gene expression in intestinal cells.},
  author={Daniel Mart{\'i}nez-Maqueda and Beatriz Miralles and Sonia de Pascual-Teresa and In{\'e}s Rever{\'o}n and Rosario Palacios Mu{\~n}oz and Isidra Recio},
  journal={Journal of agricultural and food chemistry},
  volume={60 35},
In this study, the hypothesis that food-derived opioid peptides besides β-casomorphin 7 might modulate the production of mucin via a direct action on epithelial goblet cells was investigated in HT29-MTX cells used as a model of human colonic epithelium. Seven milk whey or casein peptides, a human milk peptide, and a wheat gluten-derived peptide with proved or probable ability to bind μ- or δ-opioid receptors were tested on the cell culture. Significantly increased secretion of mucins was found… CONTINUE READING

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