Food and drug administration’s critical path initiative and innovations in drug development paradigm: Challenges, progress, and controversies


During the last decade, despite increased investment in drug research and development related activity, stagnation in new drug discovery has been documented. Despite a 70% increase in investment in research and development-related activities, a 40% fall in launch of new chemical entities was seen during 1994-2004. A steep rise in the attrition rate of drug… (More)
DOI: 10.4103/0975-7406.72130


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