Fontan and the pulmonary circulation: a potential role for new pulmonary hypertension therapies.

@article{Beghetti2010FontanAT,
  title={Fontan and the pulmonary circulation: a potential role for new pulmonary hypertension therapies.},
  author={Maurice Beghetti},
  journal={Heart},
  year={2010},
  volume={96 12},
  pages={911-6}
}
In recent decades, the Fontan procedure and its variations have resulted in markedly improved outcomes of patients with single-ventricle physiology. These improvements are expected to increase greatly the number of surviving patients, particularly those surviving long into adulthood. However, there is still a progressive risk of attrition and failure of the Fontan circulation over time, the underlying pathophysiology of which is not fully understood. Current evidence suggests that alterations… CONTINUE READING

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