Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion

@article{Hung2010FomepizoleFT,
  title={Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion},
  author={Tawny Hung and Christopher R Dewitt and W. Martz and W. Schreiber and D. Holmes},
  journal={Clinical Toxicology},
  year={2010},
  volume={48},
  pages={569 - 571}
}
  • Tawny Hung, Christopher R Dewitt, +2 authors D. Holmes
  • Published 2010
  • Medicine
  • Clinical Toxicology
  • Introduction. 2-butoxyethanol (2BE) is a solvent commonly incorporated into household and industrial cleaning products. Its ingestion causes rapid central nervous system depression, hypotension, and metabolic acidosis attributable to metabolism of the parent compound to butoxyacetic acid (BAA) by alcohol dehydrogenase. Lactic acidosis is also reported to develop in some cases. Published treatment strategies include the use of ethanol infusion, ethanol with concomitant dialysis, dialysis alone… CONTINUE READING
    6 Citations
    Chapter A 33 : Fomepizole
    Acute toxicity classification for ethylene glycol mono-n-butyl ether under the Globally Harmonized System.
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