Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion

  title={Fomepizole fails to prevent progression of acidosis in 2-butoxyethanol and ethanol coingestion},
  author={Tawny Hung and C. DeWitt and W. Martz and William Schreiber and D. Holmes},
  journal={Clinical Toxicology},
  pages={569 - 571}
Introduction. 2-butoxyethanol (2BE) is a solvent commonly incorporated into household and industrial cleaning products. Its ingestion causes rapid central nervous system depression, hypotension, and metabolic acidosis attributable to metabolism of the parent compound to butoxyacetic acid (BAA) by alcohol dehydrogenase. Lactic acidosis is also reported to develop in some cases. Published treatment strategies include the use of ethanol infusion, ethanol with concomitant dialysis, dialysis alone… Expand
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