Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.

@article{Voyaki2001FollowupOR,
  title={Follow-up of renal function in treated and untreated older patients with isolated systolic hypertension. Systolic Hypertension in Europe (Syst-Eur) Trial Investigators.},
  author={Sophia M Voyaki and Jan A Staessen and Lutgarde Thijs and J. George Wang and Aris D Efstratopoulos and Willem H. Birkenh{\"a}ger and Peter W de Leeuw and Gastonea Leonetti and Choudomir K Nachev and Jos{\'e} Luis Rodicio and Jaakko Tuomilehto and Robert H. Fagard},
  journal={Journal of hypertension},
  year={2001},
  volume={19 3},
  pages={511-9}
}
BACKGROUND In the outcome trials that provided information on renal function in older hypertensive patients, diuretics and beta-blockers were mostly used as first-line drugs. The long-term renal effects of calcium-channel blockers remain unclear. OBJECTIVE To compare the changes in renal function in 2,258 treated and 2,148 untreated patients with isolated systolic hypertension, of whom 455 had diabetes mellitus and 390 had proteinuria. METHODS We performed a post-hoc analysis of the double… CONTINUE READING

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