Follicular lymphoma with PAS-positive amorphous material: report of two cases.

@article{Harris2002FollicularLW,
  title={Follicular lymphoma with PAS-positive amorphous material: report of two cases.},
  author={James Harris and Daniel A. Cherry and John S. Lazarchick},
  journal={Annals of clinical and laboratory science},
  year={2002},
  volume={32 3},
  pages={
          299-304
        }
}
Extracellular, PAS-positive material has been described in various lymphoproliferative disorders, but is rare in malignant lymphomas. We report two such cases of grade 2 follicular lymphoma that were investigated by routine H&E histology, immunohistochemistry, flow cytometry, and molecular pathology. Ancillary studies confirmed the monoclonality in each case and the antigenic similarity to the neoplastic cells, with the exception of bcL-2. One possible pathogenic mechanism for this… CONTINUE READING

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