Follicular growth and atresia in mammalian ovaries: regulation by survival and death of granulosa cells.

@article{Matsuda2012FollicularGA,
  title={Follicular growth and atresia in mammalian ovaries: regulation by survival and death of granulosa cells.},
  author={Fuko Matsuda and Naoko Inoue and Noboru Manabe and Satoshi Ohkura},
  journal={The Journal of reproduction and development},
  year={2012},
  volume={58 1},
  pages={44-50}
}
The mammalian ovary is an extremely dynamic organ in which a large majority of follicles are effectively eliminated throughout their reproductive life. Due to the numerous efforts of researchers, mechanisms regulating follicular growth and atresia in mammalian ovaries have been clarified, not only their systemic regulation by hormones (gonadotropins) but also their intraovarian regulation by gonadal steroids, growth factors, cytokines and intracellular proteins. Granulosa cells in particular… CONTINUE READING
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