Follicular dendritic-like cells derived from human monocytes

Abstract

Follicular dendritic cells (FDCs) play a central role in controlling B-cell response maturation, isotype switching and the maintenance of B-cell memory. These functions are based on prolonged preservation of antigen and its presentation in its native form by FDCs. However, when entrapping entire pathogens, FDCs can turn into dangerous long-term reservoirs… (More)
DOI: 10.1186/1471-2172-6-23

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