Follicle culture in reproductive toxicology: a tool for in-vitro testing of ovarian function?

@article{Cortvrindt2002FollicleCI,
  title={Follicle culture in reproductive toxicology: a tool for in-vitro testing of ovarian function?},
  author={Rita G Cortvrindt and Johan E J Smitz},
  journal={Human reproduction update},
  year={2002},
  volume={8 3},
  pages={243-54}
}
Public opinion and official bodies place great emphasis on the reduction, refinement and replacement of the use of laboratory animals in testing protocols. In the field of toxicology, major efforts are being made to commit to this goal. The testing of reproductive function is currently still performed by in-vivo tests, mainly in rodents. In the past, follicle culture models were developed for the in-vitro production of mature oocytes and used to study the process of folliculogenesis and… CONTINUE READING
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