Corpus ID: 8381164

Folic acid. Monograph.

  title={Folic acid. Monograph.},
  journal={Alternative medicine review : a journal of clinical therapeutic},
  volume={10 3},
  • Published 2005
  • Medicine
  • Alternative medicine review : a journal of clinical therapeutic
Introduction Folic acid, also known generically as folate or folacin, is a member of the B-complex family of vitamins, and works in concert with vitamin B12. Folic acid functions primarily as a methyl-group donor involved in many important body processes, including DNA synthesis. Therapeutically, folic acid is instrumental in reducing homocysteine levels and the occurrence of neural tube defects. It may play a key role in preventing cervical dysplasia and protecting against neoplasia in… Expand
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Accumulation of plasma reduced folates after folic acid administration.
Repetitive oral administration every 6 hours resulted in consistently elevated levels of each metabolite pool with the same general saturation behavior as observed with single dose administration. Expand
Is disordered folate metabolism the basis for the genetic predisposition to neural tube defects?
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Molecular genetic analysis in mild hyperhomocysteinemia: a common mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for cardiovascular disease.
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