Folic acid and trastuzumab conjugated redox responsive random multiblock copolymeric nanocarriers for breast cancer therapy: In-vitro and in-vivo studies.

@article{Kumar2017FolicAA,
  title={Folic acid and trastuzumab conjugated redox responsive random multiblock copolymeric nanocarriers for breast cancer therapy: In-vitro and in-vivo studies.},
  author={Arun Kumar and Shantanu V. Lale and M. R. Aji Alex and V. Choudhary and V. Koul},
  journal={Colloids and surfaces. B, Biointerfaces},
  year={2017},
  volume={149},
  pages={
          369-378
        }
}
The study represents synthesis, characterization and biological evaluation of redox responsive polymeric nanoparticles based on random multiblock copolymer for doxorubicin delivery in breast cancer. The random multiblock copolymer was synthesized via ring opening polymerization of lactide with polyethylene glycol to form triblock copolymer followed by isomerization polymerization of the triblock copolymer and 2-hydroxyethyl disulfide with the help of hexamethylene diisocynate in presence of… Expand
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