Folic Acid Supplementation for Stroke Prevention in Patients With Cardiovascular Disease

@article{Tian2017FolicAS,
  title={Folic Acid Supplementation for Stroke Prevention in Patients With Cardiovascular Disease},
  author={Tao Tian and Kunqi Yang and Jin-Gang Cui and Lanlan Zhou and Xian-liang Zhou},
  journal={The American Journal of the Medical Sciences},
  year={2017},
  volume={354},
  pages={379–387}
}

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Folic acid supplementation is effective in stroke prevention in populations with no or partial folic acid fortification, and a greater beneficial effect was observed among trials with a lower percent use of statins.
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Folic acid supplementation did not demonstrate a major effect in averting stroke, however, potential mild benefits in primary stroke prevention, especially when folate is combined with B vitamins and in male patients, merit further investigation.
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