Folding of viral envelope glycoproteins in the endoplasmic reticulum.

@article{Braakman2000FoldingOV,
  title={Folding of viral envelope glycoproteins in the endoplasmic reticulum.},
  author={Ineke Braakman and Eelco van Anken},
  journal={Traffic},
  year={2000},
  volume={1 7},
  pages={533-9}
}
Viral glycoproteins fold and oligomerize in the endoplasmic reticulum of the host cell. They employ the cellular machinery and receive assistance from cellular folding factors. During the folding process, they are retained in the compartment and their structural quality is checked by the quality control system of the endoplasmic reticulum. A special characteristic that distinguishes viral fusion proteins from most cellular proteins is the extensive conformational change they undergo during… CONTINUE READING