Folding of lipid monolayers containing lung surfactant proteins SP-B(1-25) and SP-C studied via coarse-grained molecular dynamics simulations.

Abstract

To explore the role of lung surfactant proteins SP-B and SP-C in storing and redelivering lipid from lipid monolayers during the compression and re-expansion occurring in lungs during breathing, we simulate the folding of lipid monolayers with and without these proteins. We utilize the MARTINI coarse-grained force field to simulate monolayers containing… (More)
DOI: 10.1016/j.bbamem.2010.04.006

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