Folding into an autophagosome: ATG5 sheds light on how plants do it.

@article{Bars2014FoldingIA,
  title={Folding into an autophagosome: ATG5 sheds light on how plants do it.},
  author={Romain Le Bars and Jessica Marion and B{\'e}atrice Satiat-Jeunema{\^i}tre and Michele Wolfe Bianchi},
  journal={Autophagy},
  year={2014},
  volume={10 10},
  pages={1861-3}
}
Autophagosomes arise in yeast and animals from the sealing of a cup-shaped double-membrane precursor, the phagophore. The concerted action of about 30 evolutionarily conserved autophagy related (ATG) proteins lies at the core of this process. However, the mechanisms allowing phagophore generation and its differentiation into a sealed autophagosome are still not clear in detail, and very little is known in plants. This is due in part to the scarcity of structurally informative, real-time imaging… CONTINUE READING