Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.

@article{Simmons2003FolateRA,
  title={Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.},
  author={Graham Simmons and Andrew J Rennekamp and Ning Chai and Luk H Vandenberghe and James L Riley and Paul Bates},
  journal={Journal of virology},
  year={2003},
  volume={77 24},
  pages={13433-8}
}
Folate receptor alpha (FRalpha) has been described as a factor involved in mediating Ebola virus entry into cells (6). Furthermore, it was suggested that interaction with FRalpha results in internalization and subsequent viral ingress into the cytoplasm via caveolae (9). Descriptions of cellular receptors for Ebola virus and its entry mechanisms are of fundamental importance, particularly with the advent of vectors bearing Ebola virus glycoprotein (GP) being utilized for gene transfer into cell… CONTINUE READING
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