Folate metabolism in plants: an Arabidopsis homolog of the mammalian mitochondrial folate transporter mediates folate import into chloroplasts.

@article{Bedhomme2005FolateMI,
  title={Folate metabolism in plants: an Arabidopsis homolog of the mammalian mitochondrial folate transporter mediates folate import into chloroplasts.},
  author={Mariette Bedhomme and Michaela Hoffmann and ERIN A. MCCARTHY and Bernadette Gambonnet and Richard G. Moran and Fabrice R{\'e}beill{\'e} and St{\'e}phane Ravanel},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 41},
  pages={34823-31}
}
The distribution of folates in plant cells suggests a complex traffic of the vitamin between the organelles and the cytosol. The Arabidopsis thaliana protein AtFOLT1 encoded by the At5g66380 gene is the closest homolog of the mitochondrial folate transporters (MFTs) characterized in mammalian cells. AtFOLT1 belongs to the mitochondrial carrier family, but GFP-tagging experiments and Western blot analyses indicated that it is targeted to the envelope of chloroplasts. By using the glycine… CONTINUE READING

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