Folate mediated in vitro targeting of depolymerised trimethylated chitosan having arginine functionality.

Abstract

Delivery vectors having targeting ligands provide an impending impact on cancer gene therapy. Our work focuses on folate mediated targeting induced by conjugating poly(ethylene glycol)-folate (PEG-FA) with arginine modified chitosan polymer having low molecular weight of 15 kDa and high degree of quaternization (ATFP15H). The ATFP15H derivative on… (More)
DOI: 10.1016/j.jcis.2010.04.090

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