Folate-equipped pegylated archaeal lipid derivatives: synthesis and transfection properties.

Abstract

We have previously shown that synthetic archaeal lipid analogues are useful vectors for drug/gene delivery. We report herein the synthesis and gene transfer properties of a series of novel di- and tetraether-type archaeal derivatives with a poly(ethylene glycol) (PEG) chain and further equipped with a folic acid (FA) group. The synthetic strategy and the… (More)
DOI: 10.1002/chem.200800950

Topics

Cite this paper

@article{Lain2008FolateequippedPA, title={Folate-equipped pegylated archaeal lipid derivatives: synthesis and transfection properties.}, author={C{\'e}line Lain{\'e} and Emmanuel Mornet and Lo{\"i}c Lemi{\`e}gre and Tristan Montier and Sandrine Cammas-Marion and C{\'e}cile Neveu and Nathalie Carmoy and Pierre Lehn and Thierry Benvegnu}, journal={Chemistry}, year={2008}, volume={14 27}, pages={8330-40} }