Folate cross-feeding supports symbiotic homoacetogenic spirochetes.

@article{Graber2005FolateCS,
  title={Folate cross-feeding supports symbiotic homoacetogenic spirochetes.},
  author={Joseph R. Graber and John A. Breznak},
  journal={Applied and environmental microbiology},
  year={2005},
  volume={71 4},
  pages={
          1883-9
        }
}
Treponema primitia, an H2-consuming CO2-reducing homoacetogenic spirochete in termite hindguts, requires an exogenous source of folate for growth. Tetrahydrofolate (THF) acts as a C1 carrier in CO2-reductive acetogenesis, a microbially mediated process important to the carbon and energy requirements of termites. To examine the hypothesis that other termite gut microbes probably supply some form of folate to T. primitia in situ, we used a bioassay to screen for and isolate folate-secreting… CONTINUE READING
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