Folate and methionine metabolism in autism: a systematic review.

  title={Folate and methionine metabolism in autism: a systematic review.},
  author={Penelope A E Main and Manya Therese Angley and Philip W M Thomas and Catherine O'doherty and Michael F. Fenech},
  journal={The American journal of clinical nutrition},
  volume={91 6},
BACKGROUND Autism is a complex neurodevelopmental disorder that is increasingly being recognized as a public health issue. Recent evidence has emerged that children with autism may have altered folate or methionine metabolism, which suggests the folate-methionine cycle may play a key role in the etiology of autism. OBJECTIVE The objective was to conduct a systematic review to examine the evidence for the involvement of alterations in folate-methionine metabolism in the etiology of autism… CONTINUE READING


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