FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons

@inproceedings{Gennet2016FolR1AN,
  title={FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons},
  author={Nicole Gennet and Claudia Tamburini and Xinsheng Nan and Meng Li},
  booktitle={Scientific reports},
  year={2016}
}
Cell type-specific surface markers offer a powerful tool for purifying defined cell types for restorative therapies and drug screenings. Midbrain dopaminergic neurons (mesDA) are the nerve cells preferentially lost in the brains of Parkinson's disease patients. Clinical trials of transplantation of fetal neural precursors suggest that cell therapy may offer a cure for this devastating neurological disease. Many lines of preclinical studies demonstrate that neural progenitors committed to… CONTINUE READING
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