FolC2‐mediated folate metabolism contributes to suppression of inflammation by probiotic Lactobacillus reuteri

@inproceedings{Thomas2016FolC2mediatedFM,
  title={FolC2‐mediated folate metabolism contributes to suppression of inflammation by probiotic Lactobacillus reuteri
},
  author={Carissa M. Thomas and Delphine M. A. Saulnier and Jennifer K Spinler and Peera Hemarajata and Chunxu Gao and Sara E. Jones and Ashley Grimm and Miriam A. Balderas and Matthew D. Burstein and Christina Morra and Daniel Roeth and Markus Kalkum and James Versalovic},
  booktitle={MicrobiologyOpen},
  year={2016}
}
Bacterial-derived compounds from the intestinal microbiome modulate host mucosal immunity. Identification and mechanistic studies of these compounds provide insights into host-microbial mutualism. Specific Lactobacillus reuteri strains suppress production of the proinflammatory cytokine, tumor necrosis factor (TNF), and are protective in a mouse model of colitis. Human-derived L. reuteri strain ATCC PTA 6475 suppresses intestinal inflammation and produces 5,10-methenyltetrahydrofolic acid… CONTINUE READING
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