Foenumoside B from Lysimachia foenum-graecum inhibits adipocyte differentiation and obesity induced by high-fat diet.

Abstract

We have previously reported anti-obesity effects of Lysimachia foenum-graecum in high-fat diet (HFD)-induced obesity model. Here we isolated a triterpene saponin foenumoside B as an active component of L. foenum-graecum. Foenumoside B blocked the differentiation of 3T3-L1 preadipocytes in a dose-dependent manner with an IC50 of 0.2 μg/ml in adipogenesis… (More)
DOI: 10.1016/j.bbrc.2011.12.039

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@article{Seo2012FoenumosideBF, title={Foenumoside B from Lysimachia foenum-graecum inhibits adipocyte differentiation and obesity induced by high-fat diet.}, author={Jong Bae Seo and Sang Wook Park and Sung Sik Choe and Hyun Woo Jeong and Jae Young Park and Eun-Wook Choi and Dong-Seung Seen and Jae-Yeon Jeong and Tae - Gyu Lee}, journal={Biochemical and biophysical research communications}, year={2012}, volume={417 2}, pages={800-6} }