Focused glycomic analysis of the N-linked glycan biosynthetic pathway in ovarian cancer.

@article{Abbott2008FocusedGA,
  title={Focused glycomic analysis of the N-linked glycan biosynthetic pathway in ovarian cancer.},
  author={Karen L. Abbott and Alison V. Nairn and Erica M Hall and Marc B. Horton and John F McDonald and Kelley W Moremen and Daniela M. Dinulescu and Michael Pierce},
  journal={Proteomics},
  year={2008},
  volume={8 16},
  pages={3210-20}
}
Epithelial ovarian cancer is the deadliest female reproductive tract malignancy in Western countries. Less than 25% of cases are diagnosed when the cancer is confined, however, pointing to the critical need for early diagnostics for ovarian cancer. Identifying the changes that occur in the glycome of ovarian cancer cells may provide an avenue to develop a new generation of potential biomarkers for early detection of this disease. We performed a glycotranscriptomic analysis of endometrioid… CONTINUE READING