Focus on antioxidant enzymes and antioxidant strategies in smoking related airway diseases.

@article{Kinnula2005FocusOA,
  title={Focus on antioxidant enzymes and antioxidant strategies in smoking related airway diseases.},
  author={Vuokko L. Kinnula},
  journal={Thorax},
  year={2005},
  volume={60 8},
  pages={693-700}
}
Cigarette smoke causes significant oxidant stress which is further enhanced by recruitment and activation of inflammatory cells to the lung. Polymorphisms in some detoxification enzymes are thought to increase the risk of developing chronic obstructive pulmonary disease (COPD), but the ultimate role of genetic variability in antioxidant and/or detoxification enzymes in COPD remains obscure. Some antioxidant enzymes are inducted, but the extent of induction is insufficient to protect the lung… CONTINUE READING

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